Scream oneself hoarse - to scream very loudly.

Example: I screamed myself hoarse on the roller coaster.

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in over one's head - the situation is too difficult for you. You are in over your head when you face a challenge you are not able to meet.

The analogy is to an unskilled swimmer who has fallen into water that is too deep. Over one's head refers to the depth of the situation one is in. The situation has become more serious than the person is prepared for.

Example: The new PR Manager felt like she was in over her head during her first week at the new job.
Go ahead and lead the meeting today; I'll help you out if you get in over your head.

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hit close to home - having a direct personal effect on you

Example: Her novel about a teenager's drug addiction hit a little too close to home for my taste.
That remark about their marriage hit close to home.

Usage notes: usually said about something that upsets or embarrasses you. The noun home here means “the heart of something”.

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to bite one's tongue off - to stop yourself from saying something because it would be better not to, even if you would like to say it. This term alludes to holding the tongue between the teeth in an effort not to say something one might regret.

Example: I really wanted to tell her what I thought of him, but I had to bite my tongue off.
A new grandmother must learn to bite her tongue off so as not to give unwanted advice.
I'm sure it'll rain during graduation.—Bite your tongue off!

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give oneself over to - to devote oneself to someone or something.

Example: Laurie gave herself over to her work and soon forgot her pain.
David gave himself over to the religious order.

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to call the shots - to be the person who makes all the important decisions and who has the most power in a situation; to make the decisions; to decide what is to be done.

Example: She was used to calling the shots, to being in charge.
Sally always wants to call the shots, and Mary doesn't like to be bossed around. They don't get along well.
The company was more successful when just one or two people were calling the shots.
It's up to the boss to call the shots.

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to kiss goodbye - to be forced to regard as lost, ruined, or hopeless.
If someone tells you that you can kiss something goodbye, you have no chance of getting or having it.

Example: She can kiss her vacation plans goodbye.

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to be in the throes of something - to be experiencing a very difficult or unpleasant period; to be in the midst of a difficult struggle.

Example: The country is presently in the throes of the worst recession since the second world war.
We're in the throes of moving house at the moment.
The country was in the throes of economic collapse.
We were in the throes of giving a formal dinner when my in-laws arrived.

Usage notes: The noun throe, meaning “a severe spasm of pain,” was at first used mainly for such physical events as childbirth or dying. Today it is used both seriously and more lightly.